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MedMelano CICA Power 51% Centella Essence Regenerating Cream is a regenerating and anti-inflammatory cream in which Centella Asiatica leaf water makes up as much as 51% of the formula (30 ml). The AstaCICA™ complex (astaxanthin + centella) inhibits the secretion of pro-inflammatory cytokines and reduces redness by up to 33%.

  • Centella Asiatica Leaf Water 51% + AstaCICA™ + dipotassium glycyrrhizate, squalane and hyaluronic acid
  • Documented reduction of redness by up to 33% and restoration of the epidermal barrier
  • For sensitive, reactive skin with redness, atopic dermatitis (AD) and after dermatological procedures
  • Use daily in the morning and/or evening as the last step of skincare; customer rating 5/5

MedMelano CICA Power 51% Centella Essence Regenerating Cream – regenerating and anti-inflammatory cream, 30 ml

MedMelano CICA Power is a regenerating and anti-inflammatory cream with 51% Centella Asiatica leaf water, intended for sensitive, reactive skin with redness, atopic dermatitis (AD) and skin requiring regeneration after dermatological procedures. It soothes irritation, reduces redness and supports the rebuilding of the skin barrier.

  • Form: cream
  • Key actives: Centella Asiatica Leaf Water 51%, AstaCICA™ complex (astaxanthin + CICA), Dipotassium Glycyrrhizate, Squalane, Hyaluronic Acid
  • Indications: sensitive, reactive, dry, combination, acne-prone skin, with AD and redness, after procedures
  • Clinical effect: reduction of redness by up to 33%
  • Volume: 30 ml
  • Time of use: morning and/or evening

Description of action

MedMelano CICA Power 51% Centella Essence Regenerating Cream is built on a base of Centella Asiatica leaf water, which accounts for 51% of the composition – a concentration clearly higher than in typical CICA products, where centella extracts form the background of the composition rather than its foundation. Centella Asiatica is an ingredient with documented soothing action, supporting tissue regeneration and strengthening the epidermal barrier.

The proprietary AstaCICA™ complex combines astaxanthin – one of the stronger antioxidants used in cosmetics – with another fraction of Centella Asiatica. The combination of both ingredients strengthens protection against oxidative stress, neutralizes free radicals and accelerates the calming of inflammatory states. The manufacturer's clinical studies indicate a 33% reduction in redness. Dipotassium Glycyrrhizate, a derivative of glycyrrhizic acid, has anti-inflammatory and anti-itch effects, inhibiting the secretion of pro-inflammatory cytokines – which makes the product useful in the care of skin prone to AD and reactive redness.

The composition is complemented by squalane and hyaluronic acid, which are responsible for, respectively, lubricating the skin's lipid layer and hydrating the epidermis. Arginine supports the skin's regenerative functions. The formula contains no colorants; the product is intended both for daily care and as a regenerating preparation used directly after dermatological and aesthetic procedures.

Who it is for

  • Sensitive and reactive skin with a tendency to irritation
  • Skin with redness, rosacea or atopic dermatitis
  • Skin after invasive dermatological and aesthetic procedures (laser, peeling, microneedling)
  • Dry and combination skin requiring intensive hydration and regeneration
  • Acne-prone skin with a tendency to inflammation
  • Swollen and itchy skin requiring rapid soothing

Key active ingredients

  • Centella Asiatica Leaf Water (51%) – centella asiatica leaf water; soothes irritation, supports the regeneration of the skin barrier and has an anti-inflammatory effect.
  • AstaCICA™ complex (astaxanthin + Centella Asiatica) – a proprietary combination of a strong antioxidant with centella extract; neutralizes free radicals, soothes redness and accelerates skin regeneration.
  • Dipotassium Glycyrrhizate – a derivative of glycyrrhizic acid; has anti-inflammatory and anti-itch effects by inhibiting pro-inflammatory cytokines.
  • Squalane – lubricates the skin, strengthens the lipid protective layer of the epidermis without a heavy effect.
  • Hyaluronic Acid – binds water in the epidermis, providing long-lasting hydration.
  • Arginine – an amino acid supporting the skin's regenerative processes.

How to use

  1. Cleanse the facial skin.
  2. Apply an appropriate amount of cream to the face, neck and décolletage.
  3. Gently massage in until fully absorbed.
  4. Use daily in the morning and/or evening as the last step of your skincare routine.
  5. After dermatological procedures, you can use the cream as a regenerating dressing – in accordance with the specialist's recommendations.

Variants and complementary products

In the same cosmetic line

  • MedMelano – the manufacturer offers products from the dermocosmetic line; detailed information about other products of the brand is available on the store's website.

Frequently asked questions

For what skin type is this cream?

The cream is intended primarily for sensitive, reactive, dry, combination and acne-prone skin. It also works well for people with AD, redness and skin requiring regeneration after dermatological procedures.

Is the cream suitable for use directly after procedures such as laser or peeling?

Yes – the product is directly indicated for use after invasive dermatological and aesthetic procedures (laser, peeling, microneedling). It can be used as a regenerating dressing; the detailed post-procedure regimen should be established with a dermatologist or cosmetologist.

At what time of day should this cream be used?

The cream can be used in the morning, in the evening or at both times – daily. If you use it in the morning, remember to apply an SPF cream on top, which is not part of this product.

Does the cream reduce redness?

Yes – the manufacturer's clinical studies indicate a reduction of redness by up to 33%. This effect is primarily due to the AstaCICA™ complex and Dipotassium Glycyrrhizate, which soothe inflammatory reactions and neutralize free radicals.

How does the cream work on skin with AD and itching?

The Dipotassium Glycyrrhizate contained in the composition inhibits the secretion of pro-inflammatory cytokines, which translates into an anti-itch and anti-inflammatory effect. Squalane and hyaluronic acid additionally support the rebuilding of the skin barrier, which is weakened in the course of AD.

Can the cream be used under makeup?

The cream used in the morning can serve as the last step of skincare before makeup. Once absorbed, it provides a moisturizing and regenerating base – in this order: cream, then SPF, then makeup.

Does the product contain a UV filter?

No – MedMelano CICA Power does not contain UV filters. If you use it in your morning routine, complete your skincare with an SPF cream applied as a separate step.

Is the cream comedogenic and safe for acne?

The product is indicated, among other things, for acne-prone skin – its formula takes into account the needs of this skin. It is not labeled as comedogenic, and the active ingredients (Centella Asiatica, Dipotassium Glycyrrhizate) have a soothing effect on the inflammation typical of acne.

Composition (INCI)

Centella Asiatica Leaf Water, Aqua, Glycerin, Caprylic/Capric Triglyceride, Propanediol, Butylene Glycol, Cetearyl Alcohol, 1,2-Hexanediol, Glycereth-26, Glyceryl Stearate, Dipropylene Glycol, Squalane, Haematococcus Pluvialis Extract, Hydroxyacetophenone, Arginine, Sodium Polyacryloyldimethyl Taurate, Carbomer, Caprylyl Glycol, Hydrogenated Polydecene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Trideceth-10, Hyaluronic Acid, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Parfum

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