MedMelano CICA Power 51% Centella Essence Regenerating Cream is a regenerating and anti-inflammatory cream in which Centella Asiatica leaf water makes up as much as 51% of the formula, complemented by the AstaCICA complex and dipotassium glycyrrhizate (50 ml, PLN 198). Glycyrrhizate inhibits the pro-inflammatory cytokines IL-1beta and TNF-alpha, while astaxanthin protects cells from oxidative stress.
- 51% Centella Asiatica water instead of regular water — the maximum dose of centella in the cream base
- Inhibition of IL-1beta and TNF-alpha — real soothing of inflammation, not just alleviating symptoms
- Squalane and hyaluronic acid moisturize; the cream can act as a regenerating dressing after treatments
- For sensitive, reactive, acne-prone skin, with atopic dermatitis and redness; morning and/or evening as the last step
MedMelano CICA Power 51% Centella Essence Regenerating Cream, face cream, 50 ml
A regenerating cream with 51% Centella Asiatica leaf water and the AstaCICA™ complex, designed for sensitive, reactive skin, with redness, atopic dermatitis, and skin requiring rebuilding after dermatological treatments. It soothes inflammation, regenerates the epidermal barrier, and intensely moisturizes.
- Form: cream
- Key actives: Centella Asiatica Leaf Water 51%, AstaCICA™ complex (astaxanthin + Centella Asiatica), Dipotassium Glycyrrhizate, squalane, hyaluronic acid
- Indications: sensitive, reactive, dry, combination, acne-prone skin, with atopic dermatitis, redness, after invasive treatments
- Volume: 50 ml
- Time of use: morning and/or evening
- Application area: face, neck, décolletage
Description of action
MedMelano CICA Power 51% Centella Essence Regenerating Cream bases its action on the proprietary AstaCICA™ complex, combining astaxanthin obtained from the microalga Haematococcus pluvialis with Centella Asiatica leaf water making up as much as 51% of the composition. Centella Asiatica has long been used in dermatology as an ingredient with soothing properties that accelerate regeneration and strengthen the epidermal barrier. Astaxanthin is one of the stronger antioxidants used in cosmetology, supporting the protection of skin cells against oxidative stress.
Dipotassium Glycyrrhizate — a derivative of glycyrrhizic acid — acts at the level of inflammatory mediators: it inhibits the pro-inflammatory cytokines IL-1β and TNF-α, which translates into a reduction of redness, swelling, and irritation. This is an ingredient particularly important for skin with redness, atopic dermatitis, or skin reacting to external factors. Squalane and hyaluronic acid complement the action by rebuilding the lipid layer and maintaining an optimal level of hydration. Arginine supports regenerative processes at the cellular level.
The cream can serve as the last step of a skincare routine or as a regenerating dressing applied as needed — for example, directly after a laser treatment, chemical peel, or microneedling, when the skin requires intensive support. The formula is designed to minimize the risk of additional irritation while providing real reparative action.
Who it is for
- Sensitive and reactive skin, easily reacting with redness or burning
- Skin with atopic dermatitis (AD) requiring ingredients with anti-inflammatory action
- Skin with redness and a tendency to localized inflammation
- Dry and combination skin with a weakened epidermal barrier
- Acne-prone skin with accompanying irritation and redness
- People during or after invasive dermatological and aesthetic treatments (laser, peel, microneedling)
- Swollen and itchy skin requiring rapid soothing
Key active ingredients
- Centella Asiatica Leaf Water (51%) — centella asiatica leaf water forming the base of the formula; it soothes, has anti-inflammatory effects, and supports epidermal regeneration.
- AstaCICA™ Complex (astaxanthin + Centella Asiatica) — a proprietary complex combining the antioxidant action of astaxanthin with the reparative properties of centella; it strengthens cellular protection and regeneration of the skin barrier.
- Dipotassium Glycyrrhizate — a derivative of glycyrrhizic acid that inhibits pro-inflammatory cytokines (IL-1β, TNF-α); it reduces redness, swelling, and inflammatory reactions.
- Squalane — a lipid that restores the skin's protective layer, preventing water loss through the epidermis (TEWL).
- Hyaluronic Acid — a strong humectant that binds water in the skin structures, responsible for hydration and elasticity.
- Haematococcus Pluvialis Extract — a natural source of astaxanthin, a strong antioxidant protecting the skin against oxidative stress.
- Arginine — an amino acid supporting reparative processes and skin rebuilding.
How to use
- Cleanse the facial skin.
- Apply an appropriate amount of the cream to the face, neck, and décolletage.
- Gently massage in until absorbed.
- Use daily in the morning and/or evening as the last step of your skincare routine.
- If needed (e.g., after a dermatological treatment), the cream can be used as a regenerating dressing — applied to skin requiring intensive rebuilding.
Frequently asked questions
For what skin type is this cream?
The cream is intended primarily for sensitive, reactive, dry, combination, and acne-prone skin — that is, for a broad spectrum of skin types requiring regenerative support and soothing. It works particularly well on skin with atopic dermatitis, redness, and skin after invasive cosmetic treatments.
Is the cream suitable for use after laser treatments or peels?
Yes — the cream was also designed as a regenerating preparation after invasive dermatological and aesthetic treatments (e.g., laser, chemical peel, microneedling). It can be used as a regenerating dressing on irritated skin or skin requiring rebuilding.
Should this cream be used in the morning or evening?
The cream can be used both in the morning and in the evening — the manufacturer indicates it can be used at both times. If used in the morning, it is recommended to apply an SPF filter on top, as the cream itself does not contain sun protection.
What does Dipotassium Glycyrrhizate do in this cream?
Dipotassium Glycyrrhizate (a derivative of glycyrrhizic acid) inhibits the pro-inflammatory cytokines IL-1β and TNF-α, i.e., the mediators responsible for skin inflammation. In practice, this translates into a reduction of redness, swelling, and irritation — which is particularly important with atopic dermatitis and redness.
What is the AstaCICA™ complex?
AstaCICA™ is a proprietary complex combining astaxanthin (a strong antioxidant obtained from the microalga Haematococcus pluvialis) with Centella Asiatica. Astaxanthin protects skin cells against oxidative stress, while Centella Asiatica supports regeneration and has anti-inflammatory effects — together they strengthen the rebuilding of the epidermal barrier.
Can the cream be used on acne-prone skin?
Yes — acne-prone skin is one of the indications for using this cream. The formula contains ingredients with anti-inflammatory action (Dipotassium Glycyrrhizate, Centella Asiatica) that can help reduce the redness and irritation accompanying acne. The squalane used in the composition is a lipid considered to have a low comedogenic risk.
Can the cream be combined with retinal or acids in a routine?
A regenerating cream with Centella Asiatica is often used as a soothing preparation in routines with retinoids or acids — it is applied after the actives, as the last step of evening care. In case of irritation after using retinoids or acids, the cream can serve as a soothing dressing. There are no ingredients in the composition that conflict with these actives.
Does the cream replace serum in a routine, or should it be used alongside?
The cream can be used as a standalone final step of the routine or as a complement to serum — it does not replace it if the serum provides specific actives (e.g., vitamin C, retinol, niacinamide). The manufacturer indicates it as a preparation that closes the skincare routine or is used as a regenerating dressing after treatments.
Composition (INCI)
Centella Asiatica Leaf Water, Aqua, Glycerin, Caprylic/Capric Triglyceride, Propanediol, Butylene Glycol, Cetearyl Alcohol, 1,2-Hexanediol, Glycereth-26, Glyceryl Stearate, Dipropylene Glycol, Squalane, Haematococcus Pluvialis Extract, Hydroxyacetophenone, Arginine, Sodium Polyacryloyldimethyl Taurate, Carbomer, Caprylyl Glycol, Hydrogenated Polydecene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium EDTA, Trideceth-10, Hyaluronic Acid, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Parfum